“THE IMMUNE DOMINO Cetuximab–EGFR engagement amplifies antitumor activity 01 NK cells kill cetuximab-tagged tumor cells 02 NK-derived IFN-γ activates dendritic cells 03 Dendritic cells present tumor antigens on MHC 04 IL-12 + IL-18 reactivate NK cells and macrophages 05 Macrophages engage cetuximab–EGFR complexes, releasing IFN-γ 06 Cytotoxic T cells and other immune cells activate; macrophage CXCL signals drive chemotaxis” is a Biomedical Signal Map (DIY) efecto de texto creado con FontVibe IA.

Create a finished vertical 9:16 scientific infographic poster explaining a cetuximab–EGFR immune-activation cascade. Render every quoted line verbatim and only once. Hierarchy: large headline “THE IMMUNE DOMINO”; smaller subtitle “Cetuximab–EGFR engagement amplifies antitumor activity”; then six clearly numbered pathway labels: “01 NK cells kill cetuximab-tagged tumor cells”; “02 NK-derived IFN-γ activates dendritic cells”; “03 Dendritic cells present tumor antigens on MHC”; “04 IL-12 + IL-18 reactivate NK cells and macrophages”; “05 Macrophages engage cetuximab–EGFR complexes, releasing IFN-γ”; “06 Cytotoxic T cells and other immune cells activate; macrophage CXCL signals drive chemotaxis”. Preserve the Greek characters and punctuation exactly. Set the headline in Witch Script: a legible hand-lettered, right-slanted script with pointed capital tops, hairline upstrokes, heavier downstrokes, open counters, and a lightly hopping baseline. Restrict this script to the headline. Set the subtitle and numbered labels in a clean, highly legible, medium-weight sans serif with open apertures and generous spacing. Use a structured infographic layout: headline and subtitle at the top; a large central cutaway cell illustration in the upper-middle; six numbered explanatory rows below, aligned to a vertical connector. Make a tumor cell the central subject, marked with EGFR receptors and cetuximab antibodies at its membrane. Around it show an NK cell, dendritic cell presenting fragments from a dying tumor cell on MHC, a macrophage, and a cytotoxic T cell. Use clear directional arrows to show the cascade and a returning cytokine signal; distinguish IFN-γ, IL-12, IL-18, and CXCL with small, precise labels or matching signal marks. Do not add unsupported molecular labels or complete the unspecified CXCL subtype. Render the scientific scene as a crisp, dimensional biomedical illustration: dark midnight-blue field, fine cyan cell membranes, warm coral tumor cells, mint-green immune-cell highlights, and restrained amber cytokine particles. Use translucent membrane layers, subtle cytoplasmic texture, thin vector-like callout rules, and high-contrast edge lighting. Keep all text on clean, opaque dark panels for legibility; maintain clear separation between diagram and copy, generous margins, and a readable small-print scale. No extra text, logos, dates, or invented data.